Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 13/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954698 | 0.87 | PI4KA (0.72) | PI4KAPIK3CG | |
| SCHEMBL9953490 | 0.84 | PI4KA (0.65) | PI4KAPIK3CGUSP2CASP1ALDH1A1 | |
| SCHEMBL9953522 | 0.81 | PI4KA (0.73) | PI4KAPIK3CGCASP1MAPT | |
| SCHEMBL10288890 | 0.80 | PI4KA (0.65) | PI4KAPIK3CGALDH1A1 | |
| SCHEMBL9953082 | 0.79 | PI4KA (0.70) | PI4KAPIK3CG | |
| SCHEMBL9955594 | 0.78 | PI4KA (0.71) | PI4KAPIK3CG | |
| SCHEMBL9953192 | 0.78 | PI4KA (0.77) | PI4KAPIK3CG | |
| SCHEMBL9954652 | 0.78 | PI4KA (0.76) | PI4KAPIK3CG | |
| SCHEMBL9953916 | 0.77 | PI4KA (0.70) | PI4KAPIK3CG | |
| Lithium SCHEMBL9953931 | 0.77 | PI4KA (0.70) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |