SCHEMBL995439

SCHEMBL995439

CCCc1cnc2c(C(F)(F)F)cccc2c1OCCCCCCN1C(=O)NC(C)(c2ccc(OC(C)C)cc2)C1=O

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 20/20 0.65
NR1H3 Q13133 13/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17844086 0.93 NR1H2 (0.58) NR1H2NR1H3
SCHEMBL2350130 0.93 NR1H2 (0.57) NR1H2NR1H3
SCHEMBL12392265 0.90 NR1H2 (0.61) NR1H2NR1H3
SCHEMBL995747 0.90 NR1H2 (0.54) NR1H2NR1H3
SCHEMBL997362 0.90 NR1H2 (0.54) NR1H2NR1H3
SCHEMBL995363 0.89 NR1H2 (0.56) NR1H2NR1H3
SCHEMBL995007 0.89 NR1H2 (0.54) NR1H2NR1H3
SCHEMBL994512 0.87 NR1H2 (0.55) NR1H2NR1H3
SCHEMBL2345886 0.85 NR1H2 (0.69) NR1H2NR1H3
SCHEMBL12392280 0.84 NR1H2 (0.52) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2272843-A1 QUINOLINE COMPOUND Kowa Company, Ltd. (JP) 2011-01-12 EP disclosed