Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 18/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.63 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954007 | 0.90 | PI4KA (0.71) | PI4KAPIK3CGAXL | |
| Lithium SCHEMBL9955796 | 0.88 | PI4KA (0.57) | PI4KAPIK3CG | |
| SCHEMBL9955784 | 0.88 | PI4KA (0.57) | PI4KAPIK3CG | |
| SCHEMBL9953388 | 0.87 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL10288673 | 0.86 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL9954462 | 0.86 | PI4KA (0.56) | PI4KAPIK3CGIKBKETBK1 | |
| Lithium Ion SCHEMBL9955788 | 0.86 | PI4KA (0.55) | PI4KAPIK3CG | |
| SCHEMBL9955594 | 0.84 | PI4KA (0.71) | PI4KAPIK3CG | |
| SCHEMBL9953916 | 0.83 | PI4KA (0.70) | PI4KAPIK3CG | |
| Lithium SCHEMBL9953931 | 0.83 | PI4KA (0.70) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |