Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 19/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 16/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.68 |
| ▸ | MTOR | P42345 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953682 | 0.96 | PI4KA (0.93) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9952639 | 0.96 | PI4KA (0.92) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9953650 | 0.95 | PI4KA (0.90) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9953127 | 0.94 | PI4KA (0.89) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9954259 | 0.94 | PI4KA (0.88) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9953705 | 0.94 | PI4KA (0.88) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9953972 | 0.94 | PI4KA (0.88) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9954193 | 0.93 | PI4KA (0.87) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9953907 | 0.93 | PI4KA (0.87) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9952648 | 0.93 | PI4KA (0.87) | PI4KAPIK3CGPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |