SCHEMBL9954863

SCHEMBL9954863

Cc1ccc(-n2nccn2)c(C(=O)N2CC[C@H]3CN(c4cnc5ccccc5n4)[C@@H]3C2)c1

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 20/20 0.81
HCRTR2 O43614 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9954857 1.00 HCRTR1 (0.81) HCRTR1HCRTR2
SCHEMBL9955340 0.91 HCRTR1 (0.72) HCRTR1HCRTR2
SCHEMBL9954896 0.91 HCRTR1 (0.72) HCRTR1HCRTR2
SCHEMBL9955291 0.90 HCRTR1 (0.79) HCRTR1HCRTR2
SCHEMBL9954557 0.90 HCRTR1 (0.79) HCRTR1HCRTR2
SCHEMBL9954888 0.90 HCRTR1 (0.67) HCRTR1HCRTR2
SCHEMBL9957054 0.90 HCRTR1 (0.67) HCRTR1HCRTR2
SCHEMBL9955220 0.90 HCRTR1 (0.67) HCRTR1HCRTR2
SCHEMBL9954824 0.90 HCRTR1 (0.67) HCRTR1HCRTR2
SCHEMBL9955113 0.90 HCRTR1 (0.67) HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012085857-A1 3,8-DIAZA-BICYCLO[4.2.0]OCT-3-YL AMIDES ACTELION PHARMACEUTICALS LTD (CH) 2012-06-28 WO disclosed