SCHEMBL9955115

SCHEMBL9955115

COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1-c1ncon1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 20/20 0.62
PIK3CG P48736 17/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9955175 0.83 PI4KA (0.61) PI4KAPIK3CG
SCHEMBL10289357 0.83 PI4KA (0.61) PI4KAPIK3CG
SCHEMBL9953522 0.83 PI4KA (0.73) PI4KAPIK3CG
SCHEMBL9954338 0.83 PI4KA (0.61) PI4KAPIK3CG
SCHEMBL9953043 0.82 PI4KA (0.62) PI4KAPIK3CG
SCHEMBL9953028 0.82 PI4KA (0.50) PI4KAPIK3CG
SCHEMBL9954698 0.82 PI4KA (0.72) PI4KAPIK3CG
SCHEMBL10289042 0.82 PI4KA (0.64) PI4KAPIK3CG
SCHEMBL10288765 0.82 PI4KA (0.61) PI4KAPIK3CG
SCHEMBL9953082 0.81 PI4KA (0.70) PI4KAPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012087938-A1 QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS GLAXOSMITHKLINE LLC (US) 2012-06-28 WO disclosed
WO-2012087938-A1 QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS GLAXOSMITHKLINE LLC (US) 2012-06-28 WO disclosed