Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 16/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957258 | 0.78 | HCRTR1 (0.51) | HCRTR1HCRTR2NAAA | |
| SCHEMBL9957805 | 0.77 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL9956139 | 0.75 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL9956933 | 0.70 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL9957419 | 0.70 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL9957700 | 0.68 | HCRTR2 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL9954612 | 0.67 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL9957884 | 0.67 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL9954320 | 0.66 | HCRTR1 (0.63) | HCRTR1HCRTR2 | |
| SCHEMBL9954317 | 0.66 | HCRTR1 (0.63) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085852-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |