Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 13/20 | 0.69 |
| ▸ | GCG | P01275 | 8/20 | 0.55 |
| ▸ | GLP1R | P43220 | 2/20 | 0.48 |
| ▸ | GIPR | P48546 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951239 | 1.00 | GCGR (0.69) | GCGRGCGGLP1RGIPR | |
| SCHEMBL9956779 | 0.94 | GCGR (0.67) | GCGRGCGGLP1RGIPR | |
| SCHEMBL9950863 | 0.87 | GCGR (0.87) | GCGRGCG | |
| SCHEMBL9951094 | 0.87 | GCGR (0.87) | GCGRGCG | |
| SCHEMBL9950866 | 0.87 | GCGR (0.87) | GCGRGCG | |
| SCHEMBL9951718 | 0.87 | GCGR (0.72) | GCGRGCGGLP1RGIPR | |
| SCHEMBL9950876 | 0.87 | GCGR (0.72) | GCGRGCGGLP1RGIPR | |
| SCHEMBL9950879 | 0.87 | GCGR (0.72) | GCGRGCGGLP1RGIPR | |
| SCHEMBL9951195 | 0.85 | GCGR (0.73) | GCGRGCGGLP1RGIPR | |
| SCHEMBL9951083 | 0.85 | GCGR (0.73) | GCGRGCGGLP1RGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655331-A1 | GLUCAGON RECEPTOR MODULATORS | Pfizer Inc (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085745-A1 | GLUCAGON RECEPTOR MODULATORS | PFIZER INC. (US) | 2012-06-28 | — | — | WO | disclosed |