Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958147 | 0.94 | HCRTR1 (0.43) | HCRTR1HCRTR2DPP4DPP8DPP9 | |
| SCHEMBL9957414 | 0.91 | HCRTR1 (0.38) | HCRTR1HCRTR2DPP4DPP8DPP9 | |
| SCHEMBL9957772 | 0.90 | HCRTR1 (0.39) | HCRTR1HCRTR2DPP4DPP8DPP9 | |
| SCHEMBL9957614 | 0.87 | HCRTR1 (0.41) | HCRTR1HCRTR2DPP4DPP8DPP9 | |
| SCHEMBL9956945 | 0.79 | HCRTR1 (0.39) | HCRTR1HCRTR2DPP4DPP8DPP9 | |
| SCHEMBL9955934 | 0.72 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL9957608 | 0.72 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL9957449 | 0.71 | HCRTR2 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL9957617 | 0.71 | HCRTR1 (0.45) | HCRTR1HCRTR2DPP4DPP8DPP9 | |
| SCHEMBL9958187 | 0.69 | HCRTR1 (0.45) | HCRTR1HCRTR2DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085852-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | claimed |
| WO-2012085852-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |