Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 20/20 | 0.69 |
| ▸ | KCNJ5 | P48544 | 17/20 | 0.62 |
| ▸ | KCNJ3 | P48549 | 17/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1239284 | 0.99 | KCNA5 (0.68) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12081114 | 0.90 | KCNA5 (0.80) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12080948 | 0.89 | KCNA5 (0.69) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12081055 | 0.88 | KCNA5 (0.69) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL1239345 | 0.88 | KCNA5 (0.66) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12080311 | 0.88 | KCNA5 (0.88) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12081569 | 0.87 | KCNA5 (0.72) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12081098 | 0.87 | KCNA5 (0.74) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12080762 | 0.87 | KCNA5 (0.72) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12081057 | 0.86 | KCNA5 (0.68) | KCNA5KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467364-A2 | NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |