Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 20/20 | 0.63 |
| ▸ | KCNJ5 | P48544 | 17/20 | 0.63 |
| ▸ | KCNJ3 | P48549 | 17/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1236607 | 0.99 | KCNA5 (0.62) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12081327 | 0.89 | KCNA5 (0.78) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12081558 | 0.87 | KCNA5 (0.78) | KCNA5KCNJ5KCNJ3 | |
| Hydrochloric Acid SCHEMBL12080693 | 0.87 | KCNA5 (0.66) | KCNA5KCNJ5KCNJ3 | |
| Hydrochloric Acid SCHEMBL12079851 | 0.85 | KCNA5 (0.69) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL1239059 | 0.84 | KCNA5 (0.54) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL1239333 | 0.84 | KCNA5 (0.65) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12081216 | 0.84 | KCNA5 (0.67) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12080755 | 0.84 | KCNA5 (0.66) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12079753 | 0.83 | KCNA5 (0.79) | KCNA5KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467364-A2 | NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |