SCHEMBL9957959

SCHEMBL9957959

COC1CCOCC1.F[B-](F)(F)F.F[B-](F)(F)F.F[B-](F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.32
KAT2B Q92831 1/20 0.32
BAZ2B Q9UIF8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3143865 0.98 SYK (0.31) SYKKAT2BBAZ2B
SCHEMBL260003 0.89
Water SCHEMBL8418665 0.87
Water SCHEMBL6255194 0.87 SYK (0.31) SYKKAT2BBAZ2B
SCHEMBL9959055 0.76 DPP4 (0.31)
SCHEMBL18496219 0.76
SCHEMBL15051651 0.74
SCHEMBL760175 0.74
SCHEMBL257688 0.74
SCHEMBL257687 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1867650-B1 HYDROXYMETHYLBORON COMPOUNDS EISAI R&D MAN CO LTD (JP) 2012-06-27 EP claimed