Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218327 | 0.86 | TSHR (0.45) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL20323198 | 0.84 | HDAC6 (0.46) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL829029 | 0.83 | TSHR (0.69) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL317667 | 0.83 | TSHR (0.69) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL15223 | 0.83 | TSHR (0.69) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL23753690 | 0.83 | TSHR (0.69) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL316147 | 0.83 | TSHR (0.69) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL316163 | 0.83 | TSHR (0.69) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL20695685 | 0.83 | TSHR (0.69) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL9737629 | 0.83 | TSHR (0.69) | TSHRALDH1A1LMNAMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097458-B2 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2016-12-28 | — | — | EP | disclosed |
| EP-2121771-B2 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2016-12-07 | — | — | EP | disclosed |
| EP-2121771-B1 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2012-06-27 | — | — | EP | disclosed |