Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9959169 | 0.93 | NR1H4 (0.72) | NR1H4 | |
| SCHEMBL9958451 | 0.91 | NR1H4 (0.71) | NR1H4 | |
| SCHEMBL17128457 | 0.90 | NR1H4 (0.77) | NR1H4 | |
| SCHEMBL17128455 | 0.90 | NR1H4 (0.77) | NR1H4 | |
| SCHEMBL9952827 | 0.87 | NR1H4 (1.00) | NR1H4 | |
| SCHEMBL9958485 | 0.85 | NR1H4 (0.88) | NR1H4 | |
| SCHEMBL9959275 | 0.84 | NR1H4 (1.00) | NR1H4 | |
| SCHEMBL9952852 | 0.84 | NR1H4 (0.84) | NR1H4 | |
| SCHEMBL9951993 | 0.84 | NR1H4 (0.84) | NR1H4 | |
| SCHEMBL10086135 | 0.84 | NR1H4 (0.79) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655368-A1 | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS | IRM LLC (BM) | 2013-10-30 | — | — | EP | claimed |
| WO-2012087520-A1 | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS | IRM LLC (BM) | 2012-06-28 | — | — | WO | claimed |
| EP-2655368-A1 | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS | IRM LLC (BM) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087520-A1 | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS | IRM LLC (BM) | 2012-06-28 | — | — | WO | disclosed |