Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951923 | 0.80 | IDO1 (0.45) | IDO1GSK3BKMT2ATDO2ALDH1A1 | |
| SCHEMBL15299912 | 0.78 | IDO1 (0.41) | IDO1GSK3BKMT2ATDO2ALDH1A1 | |
| SCHEMBL15299947 | 0.77 | IDO1 (0.40) | IDO1GSK3BKMT2ATDO2ALDH1A1 | |
| SCHEMBL9951927 | 0.76 | IDO1 (0.42) | IDO1GSK3BKMT2ATDO2ALDH1A1 | |
| SCHEMBL27483539 | 0.73 | IDO1 (0.42) | IDO1GSK3BKMT2ATDO2ALDH1A1 | |
| SCHEMBL27482812 | 0.73 | IDO1 (0.42) | IDO1GSK3BKMT2ATDO2ALDH1A1 | |
| SCHEMBL30831117 | 0.72 | GSK3B (0.39) | IDO1GSK3BKMT2ATDO2ALDH1A1 | |
| SCHEMBL19463096 | 0.72 | GSK3B (0.39) | IDO1GSK3BKMT2ATDO2ALDH1A1 | |
| Potassium SCHEMBL30831182 | 0.71 | GSK3B (0.39) | IDO1GSK3BKMT2ATDO2ALDH1A1 | |
| SCHEMBL29206780 | 0.71 | GSK3B (0.39) | IDO1GSK3BKMT2ATDO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655361-B1 | PROCESS FOR THE PREPARATION OF TRIAZINYL SUBSTITUTED OXINDOLES | BAYER IP GMBH (DE) | 2016-02-24 | — | — | EP | disclosed |
| CN-103380125-B | Prepare the method for the oxindole that triazinyl replaces | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-25 | — | — | CN | disclosed |
| EP-2654421-A1 | FUSED HETEROCYCLIC INDANE CARBOXAMIDE CGRP RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2013-10-30 | — | — | EP | disclosed |
| EP-2655361-A2 | METHOD FOR PRODUCING TRIAZINYL-SUBSTITUTED OXINDOLES | Bayer Intellectual Property GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| CN-103380125-A | Method for producing triazinyl-substituted oxindoles | BAYER IP GMBH | 2013-10-30 | — | — | CN | disclosed |
| WO-2012084855-A2 | METHOD FOR PRODUCING TRIAZINYL-SUBSTITUTED OXINDOLES | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087777-A1 | FUSED HETEROCYCLIC INDANE CARBOXAMIDE CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2012-06-28 | — | — | WO | disclosed |