SCHEMBL9959535

SCHEMBL9959535

CC(C)(C)OC(=O)N[C@@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 13/20 0.53
ACE P12821 1/20 0.48
NMBR P28336 1/20 0.47
PPARA Q07869 3/20 0.44
PPARG P37231 2/20 0.44
PTPN1 P18031 1/20 0.44
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44
PPARD Q03181 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401183 1.00 SIRT2 (0.53) SIRT2ACENMBRPPARAPPARG
SCHEMBL5349888 1.00 SIRT2 (0.53) SIRT2ACENMBRPPARAPPARG
SCHEMBL29606071 0.94 SIRT2 (0.50) SIRT2ACENMBRPPARAPPARG
SCHEMBL13810396 0.92 SIRT2 (0.61) SIRT2NMBR
SCHEMBL11913040 0.92 SIRT2 (0.61) SIRT2NMBR
SCHEMBL30053690 0.90 NMBR (0.49) SIRT2NMBR
SCHEMBL28994991 0.90 SIRT2 (0.58) SIRT2NMBR
SCHEMBL28994992 0.90 SIRT2 (0.58) SIRT2NMBR
SCHEMBL18367552 0.89 SIRT2 (0.49) SIRT2NMBR
SCHEMBL29040245 0.89 SIRT2 (0.49) SIRT2NMBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600759-B2 Process of preparation of glucagon-like peptide-1 (GLP-1) receptor agonists and their analogs ENZENE BIOSCIENCES LIMITED (IN) 2026-04-14 US claimed
US-12577274-B2 Manufacture of glucagon peptides BACHEM HOLDING AG (CH) 2026-03-17 US claimed
US-20250236655-A1 PROCESS FOR THE PREPARATION OF LIRAGLUTIDE SHILPA PHARMA LIFESCIENCES LIMITED (IN) 2025-07-24 US claimed
WO-2025098464-A1 INTERMEDIATE FOR PREPARING GLUCAGON AND GLP-1 DUAL AGONIST AND PREPARATION METHOD THEREFOR INNOVENT BIOLOGICS (SUZHOU) CO., LTD. (CN) 2025-05-15 WO claimed
WO-2025094036-A1 A PROCESS FOR THE PREPARATION OF LIRAGLUTIDE PIRAMAL PHARMA LIMITED (IN) 2025-05-08 WO claimed
CN-119798083-A Iron-catalyzed aromatic compound carbon-hydrogen bond hydroxylation nitration method 南京师范大学 2025-04-11 CN claimed
CN-119798407-A Incretin analogue with multiple biological activities, synthesis method, pharmaceutical composition and application 江苏食品药品职业技术学院 2025-04-11 CN claimed
CN-119798062-A Method for catalyzing quinone hydroxylation reaction of alkene by iron 南京师范大学 2025-04-11 CN claimed
CN-119798139-A Method for synthesizing phenolic compound by iron-catalyzed hydroxylation reaction of aromatic compound 南京师范大学 2025-04-11 CN claimed
CN-114685645-B Synthetic method of somalupeptide 深圳翰宇药业股份有限公司 2025-03-21 CN claimed
EP-3433267-B1 METHOD FOR PREPARING GLUCAGON-LIKE PEPTIDES BACHEM HOLDING AG (CH) 2022-08-24 EP claimed
CN-114685645-A Synthetic method of somaglutide 深圳翰宇药业股份有限公司 2022-07-01 CN claimed
CN-112961054-B Method for iron-catalyzed ethoxycarbonyl difluoromethylation of aromatic compound 南京师范大学 2022-06-03 CN claimed
US-20220153804-A1 PROCESS OF PREPARATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR ANALOGS ENZENE BIOSCIENCES LIMITED (IN) 2022-05-19 US claimed
US-20220143150-A1 GLUCAGON-LIKE PEPTIDE-1 (GLP-1) AGONIST ANALOG, PROCESS OF PREPARATION AND USES THEREOF ENZENE BIOSCIENCES LIMITED (IN) 2022-05-12 US claimed
CN-114426441-A Method for catalyzing chlorination of quinone compounds by iron 南京师范大学 2022-05-03 CN claimed
CN-114315957-A Preparation method of polypeptide 深圳瑞德林生物技术有限公司 2022-04-12 CN claimed
CN-112480122-B Tetrahydroimidazo [1,2-a ] pyrazine compound, composition, preparation method and application thereof 中山大学 2022-03-22 CN claimed
EP-3941936-A2 PROCESS OF PREPARATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR ANALOGS Enzene Biosciences Ltd. (IN) 2022-01-26 EP claimed
CN-112961054-A Method for iron-catalyzed ethoxycarbonyl difluoromethylation of aromatic compound 南京师范大学 2021-06-15 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250236655-A1 PROCESS FOR THE PREPARATION OF LIRAGLUTIDE GLP1R, IAPP, VIP SIRT2 1051/4885ACE 1683/4885NMBR 432/4885
US-20220153804-A1 PROCESS OF PREPARATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR ANALOGS GLP1R, GIPR, GCGR SIRT2 1962/4885ACE 2676/4885NMBR 322/4885
US-12577274-B2 Manufacture of glucagon peptides IAPP, GLP1R, GCG SIRT2 3554/4885ACE 1821/4885NMBR 2223/4885
US-12600759-B2 Process of preparation of glucagon-like peptide-1 (GLP-1) receptor agonists and their analogs GLP1R, GIPR, GCG SIRT2 2276/4885ACE 2876/4885NMBR 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.