Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 12/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956818 | 0.92 | NR1H4 (0.41) | NR1H4 | |
| SCHEMBL20853741 | 0.92 | NR1H4 (0.41) | NR1H4 | |
| SCHEMBL21195665 | 0.87 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL9957585 | 0.81 | PTGDR2 (0.33) | NR1H4 | |
| SCHEMBL9957102 | 0.79 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL17839466 | 0.79 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL26922619 | 0.77 | NR1H4 (0.43) | NR1H4 | |
| SCHEMBL26923559 | 0.77 | NR1H4 (0.41) | NR1H4 | |
| SCHEMBL9957376 | 0.77 | NR1H4 (0.43) | NR1H4 | |
| SCHEMBL9960720 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655370-A1 | COMPOSITIONS AND METHODS FOR MODULATING FXR | IRM LLC (BM) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087519-A1 | COMPOSITIONS AND METHODS FOR MODULATING FXR | IRM LLC (BM) | 2012-06-28 | — | — | WO | disclosed |