SCHEMBL996

SCHEMBL996

O=[C]C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10931745 0.74
SCHEMBL11881164 0.74
Chloroform SCHEMBL11844925 0.71
SCHEMBL9152466 0.70
SCHEMBL12813492 0.70
SCHEMBL9508443 0.70
SCHEMBL29168743 0.70
SCHEMBL835425 0.70
SCHEMBL6425152 0.70
SCHEMBL3758906 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7632 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206539-A Quinolone aminothiadiazole compound and preparation method and medical application thereof 西南大学 2024-06-18 CN claimed
CN-118021978-A GHRH antagonists for use in methods of treating sarcoidosis 迈阿密大学 2024-05-14 CN claimed
WO-2024093947-A1 PRODRUG FOR DELIVERING SIRNA INTO CELL 大睿生物医药科技(上海)有限公司 2024-05-10 WO claimed
WO-2024093907-A1 LIGAND FOR DELIVERING SIRNA TO EYE AND CENTRAL NERVOUS SYSTEM 大睿生物医药科技(上海)有限公司 2024-05-10 WO claimed
CN-117843590-A 3-amino-4- (piperazin-1-yl) benzamide derivative, pharmaceutical composition containing same, and preparation method and application thereof 中国药科大学 2024-04-09 CN claimed
EP-4331674-A2 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS University of Miami (US) 2024-03-06 EP claimed
WO-2024024935-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE HAVING ANTINEOPLASTIC EFFECT 第一三共株式会社 2024-02-01 WO claimed
WO-2023183908-A1 TYK2 INHIBITOR SYNTHESIS AND INTERMEDIATES THEREOF NIMBUS LAKSHMI, INC. (US) 2023-09-28 WO claimed
EP-3999095-B1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS UNIV MIAMI (US) 2023-09-13 EP claimed
CN-114539170-B Hapten and artificial antigen for simultaneously detecting amantadine, olaquindox and chloramphenicol, and preparation method and application thereof 华南农业大学 2023-05-16 CN claimed
US-4166810-A Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide ELI LILLY AND COMPANY (US) 1979-09-04 US claimed
US-4160082-A Intermediates for aminoglycoside antibiotics PFIZER INC. (US) 1979-07-03 US claimed
US-4129731-A Process for converting 3-methylene cephalosporins to 3-heterothiomethyl cephalosporins E. R. SQUIBB & SONS, INC. (US) 1978-12-12 US claimed
US-4076819-A ANTIINFLAMMATORY AGENTS, INHIBITOR OF BLOOD PLATELET AGGREGATION PARCOR (FR) 1978-02-28 US claimed
US-4048430-A Mercaptopseudotrisaccharides SMITHKLINE CORPORATION (US) 1977-09-13 US claimed
US-3997542-A 1-(Halogenated-acetyl)-1,2,3,4-tetrahydro-6-quinolinols and esters thereof STERLING DRUG INC. (US) 1976-12-14 US claimed
US-3963695-A Tetradeoxyneamine and derivatives thereof SMITHKLINE CORPORATION (US) 1976-06-15 US claimed
US-3962253-A OXIDATION OF SELECTIVELY PROTECTED 2,3-DIHYDRO-6-METHYL-8-HYDROXY-9-ERGOLENES ELI LILLY AND COMPANY (US) 1976-06-08 US claimed
US-3960838-A Mercaptopseudodisaccharides SMITHKLINE CORPORATION (US) 1976-06-01 US claimed
US-3953422-A Deoxyglucose derivatives SMITHKLINE CORPORATION (US) 1976-04-27 US claimed