Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 18/20 | 0.59 |
| ▸ | FPR2 | P25090 | 8/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960554 | 0.85 | GRM5 (0.65) | GRM5FPR2 | |
| SCHEMBL10152388 | 0.80 | GRM5 (0.79) | GRM5FPR2 | |
| SCHEMBL11025462 | 0.79 | GRM5 (0.71) | GRM5FPR2 | |
| SCHEMBL11027838 | 0.79 | GRM5 (0.75) | GRM5FPR2 | |
| SCHEMBL11942879 | 0.79 | GRM5 (0.78) | GRM5FPR2 | |
| SCHEMBL10151947 | 0.79 | GRM5 (0.78) | GRM5FPR2 | |
| SCHEMBL10152387 | 0.79 | GRM5 (0.78) | GRM5FPR2 | |
| SCHEMBL11031816 | 0.77 | GRM5 (0.75) | GRM5FPR2HTT | |
| SCHEMBL11942910 | 0.77 | GRM5 (0.72) | GRM5FPR2HTT | |
| SCHEMBL11030627 | 0.77 | GRM5 (0.72) | GRM5FPR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654422-A1 | BICYCLO[3.2.1]OCTYL AMIDE DERIVATIVES AND USES OF SAME | H. Lundbeck A/S (DK) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088365-A1 | BICYCLO[3.2.1]OCTYL AMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2012-06-28 | — | — | WO | disclosed |