SCHEMBL9964656

SCHEMBL9964656

COC(C)COC(=O)OCCOC(=O)OCC(C)O

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
TSHR P16473 2/20 0.34
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
NFKB1 P19838 1/20 0.31
PTGS1 P23219 1/20 0.31
APEX1 P27695 1/20 0.31
THPO P40225 1/20 0.31
PMP22 Q01453 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPK1 P28482 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15315308 1.00 MAPT (0.37) MAPTTSHRHSD17B10TDP1MEN1
SCHEMBL12262433 0.94 MAPT (0.40) MAPTTSHRHSD17B10TDP1MEN1
SCHEMBL15315304 0.93 MAPT (0.33) MAPTTSHR
SCHEMBL9964651 0.93 MAPT (0.39) MAPTTSHRHSD17B10TDP1
SCHEMBL12262568 0.89 MAPT (0.37) MAPTTSHRTDP1MEN1LMNA
SCHEMBL12262574 0.88 TSHR (0.41) TSHRTDP1MEN1LMNACYP3A4
SCHEMBL9964655 0.88 MAPT (0.44) MAPTTSHRHSD17B10TDP1MEN1
SCHEMBL16589239 0.87 TDP1 (0.42) MAPTHSD17B10TDP1
SCHEMBL17194014 0.87 MAPT (0.36) MAPTTSHRTDP1MEN1LMNA
SCHEMBL12262572 0.87 MAPT (0.36) MAPTTSHRTDP1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994760-B2 Polycarbonate block copolymers SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-06-12 US disclosed
US-9884937-B2 Polymer compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-02-06 US disclosed
US-9834710-B2 Adhesive compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-12-05 US disclosed
US-20170198203-A1 POLYCARBONATE BLOCK COPOLYMERS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-07-13 US disclosed
US-9512259-B2 High strength polyurethane foam compositions and methods NOVOMER, INC. (US) 2016-12-06 US disclosed
US-20160319064-A1 POLYMER COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2016-11-03 US disclosed
US-9453100-B2 Polymer compositions and methods NOVOMER, INC. (US) 2016-09-27 US disclosed
US-20160115288-A1 CO2 CONTAINING FOAMS AND RELATED METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2016-04-28 US disclosed
US-20150344751-A1 ADHESIVE COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2015-12-03 US disclosed
US-20150307660-A1 POLYCARBONATE BLOCK COPOLYMERS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2015-10-29 US disclosed
US-20150299372-A1 HIGH STRENGTH POLYURETHANE FOAM COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2015-10-22 US disclosed
US-20150083326-A1 ADHESIVE COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2015-03-26 US disclosed
US-20140187660-A1 POLYMER COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2014-07-03 US disclosed
US-8748555-B2 Structurally precise poly(propylene carbonate) compositions NOVOMER, INC. (US) 2014-06-10 US disclosed
US-20140031453-A1 POLYCARBONATE BLOCK COPOLYMERS NOVOMER, INC. (US) 2014-01-30 US disclosed
US-20140024795-A1 ALIPHATIC POLYCARBONATE POLYOLS CONTAINING SILYL GROUPS NOVOMER, INC. (US) 2014-01-23 US disclosed
US-8580911-B2 Polycarbonate block copolymers NOVOMER, INC. (US) 2013-11-12 US disclosed
US-20130274401-A1 ADHESIVE COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-10-17 US disclosed
US-20120156410-A1 STRUCTURALLY PRECISE POLY(PROPYLENE CARBONATE) COMPOSITIONS NOVOMER, INC. (US) 2012-06-21 US disclosed
US-20110218127-A1 POLYCARBONATE BLOCK COPOLYMERS NOVOMER, INC. (US) 2011-09-08 US disclosed