Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9937445 | 0.85 | HTR2A (0.40) | HTR2AMAPTSMN1; SMN2NPSR1SOS2 | |
| SCHEMBL9938181 | 0.83 | HTR2A (0.38) | HTR2AMAPTSMN1; SMN2NPSR1SOS2 | |
| SCHEMBL26451448 | 0.77 | HTR2A (0.34) | HTR2AMAPTSMN1; SMN2NPSR1KDM4E | |
| SCHEMBL25842177 | 0.76 | CYP19A1 (0.35) | HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6282571 | 0.74 | HTR2A (0.60) | HTR2AMAPTSMN1; SMN2NPSR1HTR1D | |
| SCHEMBL26451484 | 0.73 | HTR2A (0.44) | HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL7816091 | 0.72 | NPSR1 (0.61) | HTR2AMAPTSMN1; SMN2NPSR1HTR1D | |
| SCHEMBL20553126 | 0.69 | TNF (0.44) | HTR2AMAPTNPSR1SOS2KDM4E | |
| SCHEMBL8055335 | 0.69 | HTR2A (0.73) | HTR2AMAPTSMN1; SMN2NPSR1SOS2 | |
| SCHEMBL26451454 | 0.69 | HTR2C (0.43) | HTR2AMAPTNPSR1KDM4EHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080288-A1 | 4-AMINOINDOLE DERIVATIVES AND USE THEREOF FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |