Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9964962 | 0.83 | KDM4E (0.45) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9970787 | 0.83 | POLB (0.49) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9965024 | 0.82 | KDM4E (0.38) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9964968 | 0.81 | MAPT (0.49) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9964966 | 0.81 | KDM4E (0.43) | HTR1BKDM4EGAAMEN1POLB | |
| SCHEMBL9965014 | 0.79 | SMN1; SMN2 (0.37) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9965002 | 0.77 | MEN1 (0.40) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9964989 | 0.76 | SMN1; SMN2 (0.47) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9964977 | 0.76 | MEN1 (0.73) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9964980 | 0.76 | SMN1; SMN2 (0.49) | KDM4EMEN1POLBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080288-A1 | 4-AMINOINDOLE DERIVATIVES AND USE THEREOF FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |