Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 4/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 14/20 | 0.46 |
| ▸ | TSPO | P30536 | 2/20 | 0.45 |
| ▸ | OXTR | P30559 | 6/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495998 | 0.94 | IDH1 (0.52) | IDH1AVPR1ATSPOOXTRAVPR2 | |
| SCHEMBL1495943 | 0.91 | IDH1 (0.46) | IDH1AVPR1ATSPOOXTR | |
| SCHEMBL12832110 | 0.91 | IDH1 (0.48) | IDH1AVPR1ATSPOOXTR | |
| SCHEMBL2631705 | 0.90 | AVPR1A (0.48) | IDH1AVPR1ATSPOOXTRAVPR2 | |
| Hydrochloric Acid SCHEMBL1495890 | 0.89 | AVPR1A (0.48) | IDH1AVPR1ATSPOOXTRAVPR2 | |
| SCHEMBL1495924 | 0.89 | AVPR1A (0.46) | IDH1AVPR1ATSPOOXTRAVPR2 | |
| SCHEMBL1495887 | 0.88 | AVPR1A (0.45) | IDH1AVPR1ATSPOOXTR | |
| SCHEMBL2628473 | 0.86 | IDH1 (0.52) | IDH1AVPR1ATSPOOXTRAVPR2 | |
| SCHEMBL1495930 | 0.84 | AVPR1A (0.40) | IDH1AVPR1ATSPOOXTRAVPR2 | |
| SCHEMBL1496007 | 0.83 | AVPR1A (0.42) | IDH1AVPR1ATSPOOXTRAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202858-B2 | Vasopressin V1a antagonists | VANTIA LIMITED (GB) | 2012-06-19 | — | — | US | disclosed |
| US-20090029965-A1 | Vasopressin V1a Antagonists | FERRING B.V. (NL) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029965-A1 | Vasopressin V1a Antagonists | AVPR1A, AVPR2, AVPR1B | IDH1 3133/4885AVPR1A 1/4885TSPO 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.