Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10071830 | 0.84 | SMPD1 (0.38) | SMPD1 | |
| SCHEMBL6257928 | 0.81 | SMPD1 (0.37) | SMPD1GRM4 | |
| SCHEMBL6259130 | 0.78 | SMPD1 (0.39) | SMPD1 | |
| SCHEMBL23127606 | 0.77 | SMPD1 (0.56) | SMPD1 | |
| SCHEMBL19832152 | 0.76 | SMPD1 (0.34) | SMPD1 | |
| SCHEMBL22365073 | 0.76 | GRM4 (0.41) | GRM4 | |
| SCHEMBL6719162 | 0.76 | SMPD1 (0.34) | SMPD1 | |
| SCHEMBL13095381 | 0.76 | SMPD1 (0.53) | SMPD1GRM4 | |
| SCHEMBL1923635 | 0.76 | SMPD1 (0.48) | SMPD1 | |
| SCHEMBL4185799 | 0.76 | SMPD1 (0.39) | SMPD1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120156141-A1 | NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF | GENERAL ELECTRIC COMPANY (US) | 2012-06-21 | — | — | US | disclosed |
| WO-2012080290-A1 | NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF | GENERAL ELECTRIC COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120156141-A1 | NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF | PHOSPHO1, PIK3CA, PTEN | SMPD1 3323/4885GRM4 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.