Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704499 | 0.87 | CCR1 (0.41) | CCR1GPR119MGLLSETD7MAP4K4 | |
| SCHEMBL4185696 | 0.85 | CCR1 (0.43) | CCR1GPR119MGLLSETD7MAP4K4 | |
| SCHEMBL1704705 | 0.84 | PTGDR2 (0.44) | CCR1GPR119MGLLSETD7MAP4K4 | |
| SCHEMBL29269210 | 0.83 | CCR1 (0.47) | CCR1GPR119MGLLSETD7MAP4K4 | |
| SCHEMBL29269208 | 0.83 | CCR1 (0.47) | CCR1GPR119MGLLSETD7MAP4K4 | |
| SCHEMBL29269207 | 0.83 | CCR1 (0.47) | CCR1GPR119MGLLSETD7MAP4K4 | |
| SCHEMBL377822 | 0.82 | CCR1 (0.46) | CCR1GPR119MGLLSETD7MAP4K4 | |
| SCHEMBL13954897 | 0.82 | CCR1 (0.59) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL377466 | 0.82 | CCR1 (0.46) | CCR1GPR119MGLLSETD7MAP4K4 | |
| SCHEMBL9942316 | 0.82 | KLK7 (0.37) | BCHEAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080705-A1 | IMAGING AGENTS | CHROMA THERAPEUTICS LTD (GB) | 2012-06-21 | — | — | WO | disclosed |