Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936495 | 0.91 | HDAC1 (0.52) | HDAC1IDO1HDAC3HDAC7HDAC2 | |
| SCHEMBL9936138 | 0.85 | HDAC1 (0.54) | HDAC1IDO1HDAC3HDAC7HDAC2 | |
| SCHEMBL9966446 | 0.85 | HDAC1 (0.52) | HDAC1IDO1HDAC3HDAC7HDAC2 | |
| SCHEMBL9966568 | 0.85 | HDAC1 (0.55) | HDAC1IDO1HDAC3HDAC7HDAC2 | |
| SCHEMBL9966524 | 0.84 | HDAC1 (0.49) | HDAC1IDO1HDAC3HDAC7HDAC2 | |
| SCHEMBL14295891 | 0.83 | HDAC1 (0.54) | HDAC1IDO1HDAC3HDAC7HDAC2 | |
| SCHEMBL9966418 | 0.83 | HDAC1 (0.45) | HDAC1HDAC3HDAC7HDAC2HDAC8 | |
| SCHEMBL9936886 | 0.81 | IDO1 (0.48) | HDAC1IDO1ALDH1A1HTTALOX5AP | |
| SCHEMBL14325150 | 0.81 | HDAC1 (0.46) | HDAC1IDO1HDAC3HDAC7HDAC2 | |
| SCHEMBL9966291 | 0.81 | GAA (0.46) | HDAC1IDO1ALDH1A1HTTALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |