Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966995 | 0.97 | ESR1 (0.57) | ESR1ESR2HRH3KDM4EF2 | |
| SCHEMBL9966883 | 0.95 | ESR1 (0.61) | ESR1ESR2KDM4EF2SIGMAR1 | |
| SCHEMBL9967059 | 0.90 | ESR1 (0.59) | ESR1ESR2F2LTA4H | |
| SCHEMBL9966976 | 0.90 | ESR1 (0.69) | ESR1ESR2F2 | |
| SCHEMBL9966980 | 0.89 | ESR1 (0.70) | ESR1ESR2F2 | |
| SCHEMBL9966979 | 0.89 | ESR1 (0.70) | ESR1ESR2F2 | |
| SCHEMBL9966786 | 0.88 | HRH3 (0.53) | HRH3KDM4ESIGMAR1LTA4H | |
| SCHEMBL9966977 | 0.88 | ESR1 (0.58) | ESR1ESR2F2LTA4H | |
| SCHEMBL9966816 | 0.87 | ESR1 (0.60) | ESR1ESR2F2LTA4H | |
| SCHEMBL9967000 | 0.87 | ESR1 (0.70) | ESR1ESR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |