⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643645 | 0.81 | — | — | |
| SCHEMBL1626828 | 0.79 | — | — | |
| SCHEMBL7417042 | 0.77 | — | — | |
| Methane SCHEMBL8417513 | 0.74 | — | — | |
| SCHEMBL779794 | 0.72 | — | — | |
| SCHEMBL9388781 | 0.69 | — | — | |
| SCHEMBL9326439 | 0.67 | — | — | |
| SCHEMBL10078640 | 0.65 | — | — | |
| SCHEMBL6605974 | 0.65 | TSHR (0.30) | — | |
| SCHEMBL3936228 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333552-A | β -benzo amino acid compound synthesis method | 广州安岩仁医药科技有限公司 | 2020-06-26 | — | — | CN | claimed |
| WO-2023193694-A1 | SAFE AND STABLE NIMODIPINE FORMULATION FOR INJECTION AND METHOD FOR PREPARING SAME | 上海维洱生物医药科技有限公司 | 2023-10-12 | — | — | WO | disclosed |
| CN-116635009-A | Compositions and methods for delivering anticancer agents with improved therapeutic index | 纳米科技制药公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-111333552-B | Synthesis method of beta-benzo amino acid compound | 广州安岩仁医药科技有限公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-111333552-A | β -benzo amino acid compound synthesis method | 广州安岩仁医药科技有限公司 | 2020-06-26 | — | — | CN | disclosed |
| US-10040947-B2 | Primer composition | MITSUI CHEMICALS, INC. (JP) | 2018-08-07 | — | — | US | disclosed |
| US-8765897-B2 | Hydrophilic crosslinked polymer | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20140155565-A1 | HYDROPHILIC CROSSLINKED POLYMER | MERCK PATENT GMBH (DE) | 2014-06-05 | — | — | US | disclosed |
| EP-2039683-B1 | Vasculostatic agents and methods of use thereof | TARGEGEN INC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2258780-B1 | PRIMER COMPOSITION | MITSUI CHEMICALS INC (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-7208493-B2 | Vasculostatic agents and methods of use thereof | TARGEGEN, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| WO-2006000913-A1 | METHOD FOR STERILE FILTRATION OF VISCOUS PHARMACEUTICAL COMPOSITIONS | PFIZER PRODUCTS INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050282814-A1 | Vasculostatic agents and methods of use thereof | TARGEGEN, INC. (US) | 2005-12-22 | — | — | US | disclosed |
| EP-1549614-A2 | VASCULOSTATIC AGENTS AND METHODS OF USE THEREOF | Targegen, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| EP-1517886-A1 | NOVEL PHTHALAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2005-03-30 | — | — | EP | disclosed |
| US-20040167198-A1 | Vasculostatic agents and methods of use thereof | TARGEGEN, INC. | 2004-08-26 | — | — | US | disclosed |
| WO-2004030635-A2 | VASCULOSTATIC AGENTS AND METHODS OF USE THEREOF | TARGEGEN, INC. (US) | 2004-04-15 | — | — | WO | disclosed |
| WO-2004000796-A1 | NOVEL PHTHALAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2003-12-31 | — | — | WO | disclosed |
| WO-1998037150-A1 | TRIFLUOROMETHYL-SUBSTITUTED AZO DYES | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-27 | — | — | WO | disclosed |
| US-5453186-A | Separating materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-09-26 | — | — | US | disclosed |