Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936965 | 1.00 | DOT1L (0.80) | DOT1LDNMT1 | |
| SCHEMBL9936967 | 1.00 | DOT1L (0.80) | DOT1LDNMT1 | |
| SCHEMBL15598657 | 0.95 | DOT1L (0.77) | DOT1LDNMT1 | |
| SCHEMBL15395500 | 0.89 | DOT1L (0.65) | DOT1LDNMT1 | |
| SCHEMBL9937546 | 0.89 | DOT1L (1.00) | DOT1LDNMT1 | |
| SCHEMBL9937550 | 0.89 | DOT1L (1.00) | DOT1LDNMT1 | |
| SCHEMBL9970702 | 0.88 | DOT1L (0.96) | DOT1LDNMT1 | |
| SCHEMBL9970111 | 0.88 | DOT1L (0.96) | DOT1LDNMT1 | |
| SCHEMBL15396803 | 0.88 | DOT1L (0.78) | DOT1LDNMT1 | |
| SCHEMBL15395752 | 0.88 | DOT1L (0.64) | DOT1LDNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082436-A2 | MODULATORS OF HISTONE METHYLTRANSFERASE, AND METHODS OF USE THEREOF | Epizyme, Inc. (US) | 2012-06-21 | — | — | WO | disclosed |