Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | AMD1 | P17707 | 4/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.49 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.44 |
| ▸ | GNMT | Q14749 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | NNMT | P40261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940482 | 0.98 | PI4KA (0.57) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL15395609 | 0.90 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9940545 | 0.90 | RXFP1 (0.54) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9940517 | 0.90 | RXFP1 (0.54) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9940434 | 0.89 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9937285 | 0.88 | RXFP1 (0.55) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9940605 | 0.88 | PI4KA (0.57) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9940650 | 0.87 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL954704 | 0.86 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL12915032 | 0.86 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082436-A2 | MODULATORS OF HISTONE METHYLTRANSFERASE, AND METHODS OF USE THEREOF | Epizyme, Inc. (US) | 2012-06-21 | — | — | WO | disclosed |