Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9970113 | 1.00 | DOT1L (0.75) | DOT1LDNMT1 | |
| SCHEMBL9970254 | 0.98 | DOT1L (0.76) | DOT1LDNMT1 | |
| SCHEMBL9937394 | 0.98 | DOT1L (0.76) | DOT1LDNMT1 | |
| SCHEMBL9937398 | 0.98 | DOT1L (0.76) | DOT1LDNMT1 | |
| SCHEMBL17573556 | 0.95 | DOT1L (0.73) | DOT1LDNMT1 | |
| SCHEMBL15395477 | 0.88 | DOT1L (0.61) | DOT1LDNMT1 | |
| SCHEMBL9970702 | 0.86 | DOT1L (0.96) | DOT1LDNMT1 | |
| SCHEMBL9970111 | 0.86 | DOT1L (0.96) | DOT1LDNMT1 | |
| SCHEMBL9970300 | 0.86 | DOT1L (0.61) | DOT1LDNMT1 | |
| SCHEMBL9940551 | 0.86 | DOT1L (0.61) | DOT1LDNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082436-A2 | MODULATORS OF HISTONE METHYLTRANSFERASE, AND METHODS OF USE THEREOF | Epizyme, Inc. (US) | 2012-06-21 | — | — | WO | disclosed |