Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15401218 | 1.00 | GSK3A (0.55) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL9970852 | 1.00 | GSK3A (0.55) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL15401234 | 0.92 | GSK3A (0.47) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL15401235 | 0.92 | GSK3A (0.47) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL9970851 | 0.92 | GSK3A (0.47) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL9970846 | 0.90 | GSK3A (0.59) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL15401705 | 0.90 | GSK3A (0.59) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL9967524 | 0.87 | GSK3A (0.69) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL9941874 | 0.87 | GSK3A (0.69) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL9970817 | 0.84 | GSK3A (0.49) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083121-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-21 | — | — | WO | disclosed |