Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9970881 | 1.00 | GSK3A (0.33) | GSK3AGSK3BCCNT1CDK9 | |
| SCHEMBL9970904 | 0.84 | GSK3A (0.38) | GSK3AGSK3B | |
| SCHEMBL9970877 | 0.84 | GSK3A (0.38) | GSK3AGSK3B | |
| SCHEMBL9970813 | 0.81 | GSK3A (0.36) | GSK3AGSK3B | |
| SCHEMBL15401344 | 0.81 | GSK3A (0.49) | GSK3AGSK3B | |
| SCHEMBL9941693 | 0.81 | GSK3A (0.49) | GSK3AGSK3B | |
| SCHEMBL9970817 | 0.81 | GSK3A (0.49) | GSK3AGSK3B | |
| SCHEMBL15402136 | 0.77 | GSK3A (0.42) | GSK3AGSK3B | |
| SCHEMBL15402134 | 0.77 | GSK3A (0.42) | GSK3AGSK3B | |
| SCHEMBL9967234 | 0.70 | GSK3A (0.49) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083121-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-21 | — | — | WO | disclosed |