Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.35 |
| ▸ | PRKCG | P05129 | 3/20 | 0.35 |
| ▸ | PRKCB | P05771 | 3/20 | 0.35 |
| ▸ | PRKCA | P17252 | 3/20 | 0.35 |
| ▸ | PRKCH | P24723 | 3/20 | 0.35 |
| ▸ | PRKCI | P41743 | 3/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 4/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.34 |
| ▸ | LPAR4 | Q99677 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723662 | 1.00 | TSHR (0.41) | TSHRZDHHC7PRKD3PRKCGPRKCB | |
| SCHEMBL16177286 | 0.92 | TSHR (0.37) | TSHRPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL598598 | 0.86 | TSHR (0.43) | TSHRALDH1A1LMNAFAAHADH1B | |
| SCHEMBL10608825 | 0.86 | TSHR (0.43) | TSHRALDH1A1LMNAFAAHADH1B | |
| SCHEMBL11414764 | 0.86 | TSHR (0.43) | TSHRALDH1A1LMNAFAAHADH1B | |
| SCHEMBL10795533 | 0.86 | TSHR (0.43) | TSHRALDH1A1LMNAFAAHADH1B | |
| SCHEMBL4349371 | 0.83 | — | — | |
| SCHEMBL20220546 | 0.82 | TSHR (0.50) | TSHRZDHHC7PRKD3PRKCGPRKCB | |
| SCHEMBL11742763 | 0.82 | TSHR (0.40) | TSHRALDH1A1LMNAFAAHADH1B | |
| SCHEMBL15266065 | 0.82 | TSHR (0.40) | TSHRZDHHC7ALDH1A1LMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765431-B2 | Method for enzymatic production of decarboxylated polyketides and fatty acids | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765431-B2 | Method for enzymatic production of decarboxylated polyketides and fatty acids | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765431-B2 | Method for enzymatic production of decarboxylated polyketides and fatty acids | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-07-01 | — | — | US | disclosed |
| US-20110091952-A1 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-04-21 | — | — | US | disclosed |
| US-20110091952-A1 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-04-21 | — | — | US | disclosed |
| US-20110091952-A1 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-04-21 | — | — | US | disclosed |
| WO-2011011689-A2 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-01-27 | — | — | WO | disclosed |
| WO-2011011689-A2 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110091952-A1 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | STS, COASY, SCD | TSHR 2606/4885ZDHHC7 109/4885PRKD3 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.