Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522676 | 1.00 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1TDP1 | |
| SCHEMBL14370702 | 0.95 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1TDP1 | |
| SCHEMBL19000741 | 0.95 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1TDP1 | |
| SCHEMBL18346638 | 0.95 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1TDP1 | |
| SCHEMBL13309557 | 0.95 | TDP1 (0.48) | MEN1KMT2ATSHRMAPK1TDP1 | |
| SCHEMBL94032 | 0.95 | TDP1 (0.48) | MEN1KMT2ATSHRMAPK1TDP1 | |
| SCHEMBL17614754 | 0.91 | TDP1 (0.47) | MEN1KMT2ATSHRMAPK1TDP1 | |
| SCHEMBL30946742 | 0.91 | TDP1 (0.47) | MEN1KMT2ATSHRMAPK1TDP1 | |
| SCHEMBL30946744 | 0.91 | TDP1 (0.47) | MEN1KMT2ATSHRMAPK1TDP1 | |
| SCHEMBL30946745 | 0.91 | TDP1 (0.47) | MEN1KMT2ATSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377464-B2 | Polymerizable surfactants and their use as device forming comonomers | BAUSCH & LOMB INCORPORATED (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120157565-A1 | Polymerizable Surfactants and Their Use as Device Forming Comonomers | BAUSCH HEALTH US, LLC | 2012-06-21 | — | — | US | disclosed |