SCHEMBL9972382

SCHEMBL9972382

C=C(C)C(=O)OCCCCC(=O)OC1C[C@H](OC(=O)CCCCOC(=O)C(=C)C)[C@H](OC(=O)CCCCOC(=O)C(=C)C)CO1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
THRB P10828 1/20 0.33
PRKCA P17252 5/20 0.30
BCHE P06276 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9912658 1.00 TSHR (0.41) TSHRALDH1A1POLBAPEX1HTT
SCHEMBL19697195 1.00 TSHR (0.41) TSHRALDH1A1POLBAPEX1HTT
SCHEMBL20842568 1.00 TSHR (0.41) TSHRALDH1A1POLBAPEX1HTT
SCHEMBL18083264 0.95 TSHR (0.38) TSHRALDH1A1POLBAPEX1HTT
SCHEMBL18869300 0.94 TSHR (0.40) TSHRALDH1A1POLBAPEX1HTT
SCHEMBL19155275 0.92 TSHR (0.36) TSHRALDH1A1POLBAPEX1HTT
SCHEMBL19697388 0.92 TSHR (0.36) TSHRALDH1A1POLBAPEX1HTT
SCHEMBL18472730 0.90 TSHR (0.34) TSHRALDH1A1
SCHEMBL22426048 0.89 TSHR (0.38) TSHRALDH1A1POLBAPEX1HTT
SCHEMBL18522704 0.88 TSHR (0.34) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10934487-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2021-03-02 US disclosed
EP-3248060-B1 LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2020-09-02 EP disclosed
US-10550327-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2020-02-04 US disclosed
US-20180223187-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2018-08-09 US disclosed
US-20180208848-A1 LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2018-07-26 US disclosed
US-20180187081-A1 PROCESS OF PREPARING A LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2018-07-05 US disclosed
US-20180188586-A1 PROCESS OF PREPARING A LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2018-07-05 US disclosed
EP-2703472-B1 Liquid crystalline medium MERCK PATENT GMBH (DE) 2018-07-04 EP disclosed
US-20180171231-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-21 US disclosed
US-9982194-B2 Liquid-crystalline media MERECK PATENT GMBH (DE) 2018-05-29 US disclosed
WO-2013124040-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2013-08-29 WO disclosed
US-20130207038-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20130207038-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20130183460-A1 LIQUID-CRYSTALLINE MEDIA MERCK PATENT GMBH (DE) 2013-07-18 US disclosed
US-20130183460-A1 LIQUID-CRYSTALLINE MEDIA MERCK PATENT GMBH (DE) 2013-07-18 US disclosed
US-20130037745-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-02-14 US disclosed
US-20130037745-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-02-14 US disclosed
WO-2012130380-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-10-04 WO disclosed
WO-2012097858-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2012-07-26 WO disclosed
WO-2012079710-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-06-21 WO disclosed