Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE8B | O95263 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9972616 | 1.00 | ATM (0.40) | ATMHSD17B10ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL16538867 | 0.89 | ATM (0.37) | ATMHSD17B10ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL16538787 | 0.89 | ATM (0.40) | ATMHSD17B10ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL16538597 | 0.89 | ATM (0.40) | ATMHSD17B10ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL16551792 | 0.88 | ATM (0.37) | ATMHSD17B10ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL16551819 | 0.88 | ATM (0.37) | ATMHSD17B10ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL16538727 | 0.86 | ATM (0.40) | ATMHSD17B10ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL16551798 | 0.86 | ATM (0.40) | ATMHSD17B10ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL16551813 | 0.86 | ATM (0.40) | ATMHSD17B10ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL16551796 | 0.86 | ATM (0.40) | ATMHSD17B10ALOX5APFEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157421-A1 | 17Beta-Alkyl-17Alpha-oxy-estratrienes | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-21 | — | — | US | disclosed |
| US-20120157421-A1 | 17Beta-Alkyl-17Alpha-oxy-estratrienes | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-21 | — | — | US | disclosed |
| WO-2010139411-A2 | 17β-ALKYL-17α-OXY-ESTRATRIENES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-09 | — | — | WO | disclosed |
| EP-2258375-A1 | 17B-alkyl-17alpha-oxy-estratrienes | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157421-A1 | 17Beta-Alkyl-17Alpha-oxy-estratrienes | CYP19A1, HSD17B11, CYP17A1 | ATM 4763/4885HSD17B10 58/4885ALOX5AP 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.