SCHEMBL99730

SCHEMBL99730

CCCC[CH]CCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.55
THRB P10828 1/20 0.53
FAAH O00519 2/20 0.48
TRPV1 Q8NER1 1/20 0.48
DNM1 Q05193 3/20 0.47
ALDH1A1 P00352 1/20 0.45
EP300 Q09472 1/20 0.42
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL102326 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL201880 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL99494 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25170900 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL201327 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25176506 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25170220 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25170905 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL100509 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL103528 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1995274-A1 Method for preparing nanotube pre-composites, in particular made from carbon ARKEMA FRANCE (FR) 2008-11-26 EP claimed
EP-1558206-A1 FORMULATIONS FOR TOPICAL DELIVERY OF BIOACTIVE SUBSTANCES AND METHODS FOR THEIR USE Australian Importers, Ltd (US) 2005-08-03 EP claimed
WO-2004039348-A1 FORMULATIONS FOR TOPICAL DELIVERY OF BIOACTIVE SUBSTANCES AND METHODS FOR THEIR USE AUSTRALIAN IMPORTERS, LTD. (US) 2004-05-13 WO claimed
US-20040081681-A1 Anhydrous formulations for percutaneous absorption AUSTRALIAN IMPORTERS 2004-04-29 US claimed
CN-118355051-A Polycarbonate resin composition 三菱化学株式会社 2024-07-16 CN disclosed
CN-118215472-A Lipid nanoparticles for oligonucleotide delivery 纪费亚斯公司 2024-06-18 CN disclosed
CN-118215471-A Lipid nanoparticles for oligonucleotide delivery 纪费亚斯公司 2024-06-18 CN disclosed
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
CN-117916286-A Polycarbonate resin composition 三菱化学株式会社 2024-04-19 CN disclosed
CN-117858888-A Intravitreal mitochondrial targeting peptide prodrugs and methods of use thereof 艾迪雅生物有限责任公司 2024-04-09 CN disclosed
WO-2024071045-A1 POLYCARBONATE RESIN AND MOLDED ARTICLE CONTAINING SAME 富士フイルム株式会社 2024-04-04 WO disclosed
CN-117598918-A Moisturizing composition and preparation method and application thereof 诗理(上海)生物科技有限公司 2024-02-27 CN disclosed
CN-86104185-A The preparation technology and the medicinal use thereof of N-(2-aminoacyl amino-2-deoxidation-hexose-based)-amides, amino formate and a ureas 1987-04-08 CN disclosed
EP-0206037-A2 Carbamates and ureas of N-(2-aminoacylamido-2-desoxy-hexosyl) amide, method for their preparation and their pharmaceutical use BAYER AG (DE) 1986-12-30 EP disclosed
US-4396519-A Alkyl-substituted bicycloalkyl ethers as useful lubricants and lubricating oils containing said ethers TEXACO INC. (US) 1983-08-02 US disclosed
US-4365096-A Alkyl-substituted bicycloalkyl ethers TEXACO INC. (US) 1982-12-21 US disclosed
US-4341858-A SILVER HALIDE LAYER INCLUDING AN OXIDIZER TO PROMOTE NUCLEATION; PHOTOGRAPHIC COLOR FILMS EASTMAN KODAK COMPANY (US) 1982-07-27 US disclosed
US-4089868-A Sulfonium salt substantive sunscreen materials COLGATE-PALMOLIVE COMPANY (US) 1978-05-16 US disclosed
US-4045549-A Sulfonium salt substantive sunscreen compositions COLGATE-PALMOLIVE COMPANY (US) 1977-08-30 US disclosed
US-4022829-A INTERMEDIATES FOR SUNSCREEN AGENTS COLGATE-PALMOLIVE COMPANY (US) 1977-05-10 US disclosed