Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 17/20 | 0.60 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995440 | 1.00 | NR1H2 (0.60) | NR1H2NR1H3L3MBTL1MAPTHTT | |
| SCHEMBL995268 | 0.99 | NR1H2 (0.60) | NR1H2NR1H3L3MBTL1MAPTHTT | |
| SCHEMBL994870 | 0.96 | NR1H2 (0.55) | NR1H2NR1H3L3MBTL1HTT | |
| SCHEMBL993843 | 0.96 | NR1H2 (0.55) | NR1H2NR1H3L3MBTL1HTT | |
| SCHEMBL997060 | 0.96 | NR1H2 (0.55) | NR1H2NR1H3L3MBTL1HTT | |
| SCHEMBL994604 | 0.92 | NR1H2 (0.56) | NR1H2NR1H3L3MBTL1MAPT | |
| SCHEMBL994742 | 0.92 | NR1H2 (0.56) | NR1H2NR1H3L3MBTL1MAPT | |
| SCHEMBL12392141 | 0.91 | NR1H2 (0.52) | NR1H2NR1H3L3MBTL1MAPTHTT | |
| SCHEMBL12392087 | 0.91 | NR1H2 (0.52) | NR1H2NR1H3L3MBTL1MAPTHTT | |
| SCHEMBL994412 | 0.91 | NR1H2 (0.56) | NR1H2NR1H3L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008306-B2 | Quinoline compounds | KOWA COMPANY, LTD. (JP) | 2011-08-30 | — | — | US | disclosed |
| EP-2272843-A1 | QUINOLINE COMPOUND | Kowa Company, Ltd. (JP) | 2011-01-12 | — | — | EP | disclosed |