⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9974744 | 0.78 | — | — | |
| SCHEMBL22932558 | 0.71 | — | — | |
| SCHEMBL9407872 | 0.69 | — | — | |
| SCHEMBL22458667 | 0.66 | — | — | |
| SCHEMBL17512746 | 0.64 | — | — | |
| SCHEMBL19558005 | 0.64 | — | — | |
| SCHEMBL8130460 | 0.61 | — | — | |
| SCHEMBL19557999 | 0.61 | — | — | |
| SCHEMBL19145707 | 0.60 | MAPT (0.33) | — | |
| SCHEMBL23346671 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318140-B9 | NOVEL AMIDE DERIVATIVES AND MEDICINAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2014-05-21 | — | — | EP | disclosed |
| EP-1318140-B1 | NOVEL AMIDE DERIVATIVES AND MEDICINAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-05-18 | — | — | EP | disclosed |