Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9974921 | 0.92 | CYP19A1 (0.51) | CYP11B1CYP11B2MKNK1MKNK2CYP19A1 | |
| SCHEMBL9974980 | 0.88 | CYP2A6 (0.58) | CYP11B1CYP11B2MKNK1MKNK2CYP19A1 | |
| SCHEMBL9974910 | 0.87 | CYP11B1 (0.51) | CYP11B1CYP11B2ALDH1A1FYNHSD17B1 | |
| SCHEMBL6279050 | 0.87 | CYP2A6 (0.63) | CYP11B1CYP11B2MKNK1MKNK2CYP19A1 | |
| SCHEMBL9974924 | 0.87 | CYP2A6 (0.62) | CYP11B1CYP11B2MKNK1MKNK2CYP19A1 | |
| SCHEMBL9974947 | 0.87 | CYP2A6 (0.62) | CYP11B1CYP11B2MKNK1MKNK2CYP19A1 | |
| SCHEMBL23487539 | 0.86 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP19A1DHODHCYP2A6 | |
| SCHEMBL9974981 | 0.86 | CYP2A6 (0.69) | CYP11B1CYP11B2MKNK1MKNK2CYP19A1 | |
| SCHEMBL15459109 | 0.85 | CYP2A6 (0.58) | CYP11B1CYP11B2MKNK1MKNK2CYP19A1 | |
| SCHEMBL15459160 | 0.85 | CYP2A6 (0.58) | CYP11B1CYP11B2MKNK1MKNK2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081541-A1 | 1, 2, 4, 5-SUBSTITUTED PHENYL DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |