Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 13/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28547043 | 0.91 | PDK2 (0.44) | PDK2CLK4 | |
| SCHEMBL30601319 | 0.91 | PDK2 (0.44) | PDK2CLK4 | |
| SCHEMBL14508155 | 0.90 | PDK2 (0.40) | PDK2RARBRARGRXRA | |
| SCHEMBL14508195 | 0.90 | PDK2 (0.40) | PDK2RARBRARGRXRA | |
| SCHEMBL14508230 | 0.90 | PDK2 (0.42) | PDK2CLK4RARBRARGRXRA | |
| SCHEMBL14508218 | 0.90 | PDK2 (0.42) | PDK2CLK4RARBRARGRXRA | |
| SCHEMBL14508235 | 0.90 | PDK2 (0.40) | PDK2RARBRARGRXRA | |
| SCHEMBL13388991 | 0.89 | PDK2 (0.44) | PDK2CLK4 | |
| SCHEMBL9974937 | 0.87 | PDK2 (0.52) | PDK2EDNRBEDNRATNKS | |
| SCHEMBL14508164 | 0.87 | PDK2 (0.42) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081541-A1 | 1, 2, 4, 5-SUBSTITUTED PHENYL DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |