Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9937587 | 0.93 | TTK (0.82) | TTK | |
| SCHEMBL9938641 | 0.86 | TTK (0.81) | TTK | |
| SCHEMBL15843853 | 0.85 | TTK (0.85) | TTK | |
| SCHEMBL9936508 | 0.84 | TTK (0.88) | TTK | |
| SCHEMBL15843830 | 0.84 | TTK (0.87) | TTK | |
| SCHEMBL15843872 | 0.83 | TTK (0.89) | TTK | |
| SCHEMBL9936559 | 0.83 | TTK (1.00) | TTK | |
| SCHEMBL9936310 | 0.82 | TTK (1.00) | TTK | |
| SCHEMBL15843961 | 0.82 | TTK (0.80) | TTK | |
| SCHEMBL9942750 | 0.82 | TTK (0.83) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080236-A1 | 6-SUBSTITUTED IMIDAZOPYRAZINES FOR USE AS MPS-1 AND TKK INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-21 | — | — | WO | disclosed |