Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | APAF1 | O14727 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19194091 | 0.86 | BIRC5 (0.56) | MAPTHTTMAPK1APAF1THRB | |
| SCHEMBL11714303 | 0.82 | HTT (0.49) | MAPTHTTMAPK1APAF1THRB | |
| SCHEMBL4019008 | 0.82 | HTT (0.62) | MAPTHTTMAPK1APAF1THRB | |
| SCHEMBL9359369 | 0.81 | HTT (0.61) | MAPTHTTMAPK1APAF1THRB | |
| SCHEMBL8757800 | 0.81 | HTT (0.61) | MAPTHTTMAPK1APAF1THRB | |
| SCHEMBL8681872 | 0.81 | HTT (0.54) | MAPTHTTMAPK1APAF1THRB | |
| SCHEMBL11262533 | 0.80 | HTT (0.67) | MAPTHTTMAPK1APAF1THRB | |
| SCHEMBL31540570 | 0.79 | HTT (0.53) | MAPTHTTMAPK1APAF1THRB | |
| SCHEMBL13808442 | 0.78 | MEN1 (0.46) | MAPTHTTMAPK1APAF1THRB | |
| SCHEMBL10899000 | 0.78 | HTT (0.57) | MAPTHTTMAPK1APAF1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080152-A1 | USE OF SUBSTITUTED METHOXYHYDROXYPHENYLALKYL DERIVATIVES AS PRESERVATIVE AND PRESERVING METHOD | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |