⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10614591 | 1.00 | — | — | |
| SCHEMBL9975570 | 1.00 | — | — | |
| SCHEMBL14445073 | 0.82 | MAPT (0.42) | — | |
| SCHEMBL6755678 | 0.82 | — | — | |
| SCHEMBL10828218 | 0.81 | TSHR (0.39) | — | |
| SCHEMBL12283742 | 0.81 | TSHR (0.39) | — | |
| SCHEMBL22037290 | 0.81 | — | — | |
| SCHEMBL8373589 | 0.79 | MAPT (0.40) | — | |
| SCHEMBL3373145 | 0.79 | GAA (0.45) | — | |
| SCHEMBL738915 | 0.79 | MAPT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9440958-B2 | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | INCYTE CORPORATION (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150025056-A1 | SUBSTITUTED CYCLIC HYDROXAMATES AS INHIBITORS OF MATRIX METALLOPROTEINASES | INCYTE CORPORATION (US) | 2015-01-22 | — | — | US | disclosed |
| US-8853243-B2 | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | INCYTE CORPORATION (US) | 2014-10-07 | — | — | US | disclosed |
| US-8202893-B2 | Cannabinergic lipid ligands | UNIVERSITY OF CONNECTICUT (US) | 2012-06-19 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-20090198052-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE PIPERIDINE COMPOUNDS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-06 | — | — | US | disclosed |
| US-20090198052-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE PIPERIDINE COMPOUNDS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-06 | — | — | US | disclosed |
| US-20090163557-A1 | Cannabinergic Lipid Ligands | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-06-25 | — | — | US | disclosed |
| EP-2022782-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PIPERIDINE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2009-02-11 | — | — | EP | disclosed |
| US-7390905-B2 | Piperidine compound and process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-24 | — | — | US | disclosed |
| US-7390905-B2 | Piperidine compound and process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-24 | — | — | US | disclosed |
| US-20070112029-A1 | Piperidine compound and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
| US-20070112029-A1 | Piperidine compound and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |