Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10324943 | 0.93 | GRM4 (0.34) | GRM4ROCK2GRM1PARP1 | |
| SCHEMBL10325384 | 0.86 | NAMPT (0.35) | PTPN1GRM4MAPTROCK2TP53 | |
| SCHEMBL9941709 | 0.81 | KDM4E (0.46) | MAPTTP53KDM4EHTTATM | |
| SCHEMBL10325054 | 0.80 | KMT2A (0.35) | GRM4MAPTTP53KDM4ERXFP1 | |
| SCHEMBL10365294 | 0.80 | NAMPT (0.36) | GRM4ROCK2 | |
| SCHEMBL16866379 | 0.79 | NAMPT (0.35) | PTPN1GRM4MAPTROCK2TP53 | |
| SCHEMBL10366103 | 0.79 | NAMPT (0.35) | GRM4ROCK2GRM1 | |
| SCHEMBL10324459 | 0.79 | NAMPT (0.35) | GRM4ROCK2GRM1 | |
| SCHEMBL10324542 | 0.79 | NAMPT (0.35) | PTPN1GRM4MAPTROCK2TP53 | |
| SCHEMBL10324335 | 0.79 | NAMPT (0.32) | GRM4ROCK2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083105-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL DISCOVERY, INC. (US) | 2012-06-21 | — | — | WO | disclosed |