Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976198 | 0.92 | AKT1 (0.79) | AKT1 | |
| SCHEMBL15395260 | 0.89 | AKT1 (1.00) | AKT1 | |
| Hydrochloric Acid SCHEMBL15388053 | 0.88 | AKT1 (0.98) | AKT1 | |
| SCHEMBL15388312 | 0.87 | AKT1 (1.00) | AKT1 | |
| SCHEMBL9976115 | 0.84 | AKT1 (1.00) | AKT1 | |
| SCHEMBL9975955 | 0.84 | AKT1 (1.00) | AKT1 | |
| SCHEMBL9976147 | 0.84 | AKT1 (1.00) | AKT1 | |
| SCHEMBL15388195 | 0.84 | AKT1 (1.00) | AKT1 | |
| SCHEMBL15388132 | 0.84 | AKT1 (0.76) | AKT1 | |
| SCHEMBL9976106 | 0.84 | AKT1 (1.00) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080237-A1 | SUBSTITUTED PYRIMIDO[1,2-B]INDAZOLES AND THEIR USE AS MODULATORS OF THE PI3K/AKT PATHWAY | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-21 | — | — | WO | disclosed |