Sugi Predict

Sugi Predict / Compounds / SCHEMBL9976495

SCHEMBL9976495

SCHEMBL9976495

CN1CCCN(c2ccc(C(=O)Nc3c(O)cccc3C(=O)Nc3ccc(Cl)cc3)s2)CC1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 19/20 0.70
▸ ESRRG P62508 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9976503 0.92 F10 (0.70) F10ESRRG
SCHEMBL9979769 0.90 F10 (0.71) F10
SCHEMBL9976504 0.89 F10 (0.72) F10
SCHEMBL5399426 0.83 F10 (1.00) F10
SCHEMBL9976499 0.79 F10 (0.76) F10
SCHEMBL9976496 0.79 F10 (0.72) F10
SCHEMBL9979770 0.76 F10 (0.76) F10
SCHEMBL9976455 0.74 F10 (1.00) F10
SCHEMBL5409814 0.73 F10 (0.84) F10
SCHEMBL9928647 0.73 F10 (0.84) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE43481-E1 Diazepan derivatives or salts thereof ASTELLAS PHARMA INC. (JP) 2012-06-19 — — US disclosed
US-RE43481-E1 Diazepan derivatives or salts thereof ASTELLAS PHARMA INC. (JP) 2012-06-19 — — US disclosed
US-7307074-B2 Activated blood coagulation factor X inhibitor and also to such a pharmaceutical agent and particularly has an excellent activity by oral administration ASTELLAS PHARMA INC. (JP) 2007-12-11 — — US disclosed
US-7307074-B2 Activated blood coagulation factor X inhibitor and also to such a pharmaceutical agent and particularly has an excellent activity by oral administration ASTELLAS PHARMA INC. (JP) 2007-12-11 — — US disclosed