SCHEMBL9976901

SCHEMBL9976901

c1ccc2c(c1)ccc1cc(-c3ccc(-c4ccc5ccc6cccnc6c5n4)cc3)c3ccccc3c12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.43
CCR8 P51685 5/20 0.43
KDM4E B2RXH2 3/20 0.43
MAPT P10636 3/20 0.43
CCR5 P51681 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
LMNA P02545 2/20 0.43
CYP3A4 P08684 2/20 0.43
TP53 P04637 2/20 0.43
GMNN O75496 1/20 0.43
HSP90AA1 P07900 1/20 0.43
MMP2 P08253 1/20 0.43
CYP2D6 P10635 1/20 0.43
MMP9 P14780 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
MMP8 P22894 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17899311 0.90 KDM4E (0.47) KDM4EMAPTSMN1; SMN2TDP1ALDH1A1
SCHEMBL9976900 0.89 MAPT (0.48) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL9611817 0.88 CCR1 (0.44) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL23370571 0.87 CYP11B1 (0.53) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17691967 0.87 CCR1 (0.41) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL12954935 0.86 CCR1 (0.43) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17899293 0.86 CYP11B1 (0.51) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL22617882 0.85 CCR1 (0.37) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL12451879 0.85 CCR1 (0.44) CCR1CCR8KDM4EMAPTCCR5
SCHEMBL17691971 0.85 MAPT (0.47) CCR1CCR8KDM4EMAPTCCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552259-B1 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20220393113-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-08 US disclosed
US-RE47654-E1 Organic electroluminescence device IDEMITSU KOASN CO., LTD. (JP) 2019-10-22 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-9126943-B2 Nitrogenated heterocyclic ring derivative and organic electroluminescent element comprising same IDEMITSU KOSAN CO., LTD. (JP) 2015-09-08 US disclosed
US-9126943-B2 Nitrogenated heterocyclic ring derivative and organic electroluminescent element comprising same IDEMITSU KOSAN CO., LTD. (JP) 2015-09-08 US disclosed
US-8803420-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-08-12 US disclosed
US-8803420-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-08-12 US disclosed
US-20120153268-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-21 US disclosed
US-20120153268-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-21 US disclosed