SCHEMBL9976972

SCHEMBL9976972

Cc1nc2ccccc2n1-c1ccc(-c2ccc3c4c(cccc24)-c2c-3c(-c3ccccc3)c3ccccc3c2-c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.52
HTT P42858 1/20 0.52
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.38
KDM4E B2RXH2 2/20 0.38
POLB P06746 2/20 0.38
HSD17B10 Q99714 2/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
RECQL P46063 1/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
RAB9A P51151 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9976975 0.90 ESR1 (0.53) MAPK1HTTESR1ESR2ALDH1A1
SCHEMBL9976983 0.89 ESR1 (0.52) MAPK1HTTESR1ESR2ALDH1A1
SCHEMBL9611842 0.88 MAPK1 (0.56) MAPK1HTTESR1ESR2TSHR
SCHEMBL9976978 0.88 KDM4E (0.41) MAPK1HTTESR1ESR2TSHR
SCHEMBL9976977 0.88 ESR1 (0.50) MAPK1HTTESR1ESR2ALDH1A1
SCHEMBL21392415 0.87 MAPK1 (0.61) MAPK1HTTESR1ESR2TSHR
SCHEMBL9611865 0.86 ESR1 (0.54) MAPK1HTTESR1ESR2ALDH1A1
SCHEMBL21392572 0.86 MAPK1 (0.51) MAPK1HTTESR1ESR2TSHR
SCHEMBL10019157 0.85 TSHR (0.45) MAPK1HTTESR1ESR2TSHR
SCHEMBL2604819 0.85 MAPK1 (0.58) MAPK1HTTESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE47654-E1 Organic electroluminescence device IDEMITSU KOASN CO., LTD. (JP) 2019-10-22 US disclosed
EP-2525425-B1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO (JP) 2014-10-15 EP disclosed
US-8803420-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-08-12 US disclosed
US-8803420-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-08-12 US disclosed
EP-2525425-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd. (JP) 2012-11-21 EP disclosed
US-20120153268-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-21 US disclosed
US-20120153268-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-21 US disclosed